منابع مشابه
Healing hearts and fighting fat
T cell receptors (TCRs) band together to detect minute amounts of antigen, according to Schamel and colleagues on page 493. Their new work shows that TCRs are expressed on the surface of resting T cells either individually or in groups. The grouped TCRs, but not the solitary receptors, were triggered by low dose antigen, suggesting that these receptors must cooperate when antigen is scarce. Whe...
متن کاملMyocardial electrical impedance mapping of ischemic sheep hearts and healing aneurysms.
BACKGROUND This study was designed to examine the bulk electrical properties of myocardium and their variation with the evolution of infarction after coronary occlusion. These properties may be useful in distinguishing between normal, ischemic, and infarcted tissue on the basis of electrophysiological parameters. METHODS AND RESULTS The electrical impedance of myocardial tissue was studied in...
متن کاملRegenerative healing of incisional wounds in midgestational murine hearts in organ culture.
OBJECTIVE Using an organ-culture fetal heart repair model, we explored fetal repair in tissues other than dermis. METHODS Wounded fetal mouse hearts of 14 and 18 days' gestation (term = 20 days), as well as hearts of 22 days' gestation (newborn), were maintained in serum-free medium. Specimens were fixed at 2, 7, and 11 days and then processed for histologic examination. Small fragments of fe...
متن کامل“Rusty Hearts”
Rapidly restoring blood flow in the epicardial coronary artery after an acute obstruction is critical for limiting myocardial tissue damage and salvaging the area at risk. Minimizing the acute injury to the myocardium after an ischemic event (ie, infarct size) has been strongly correlated with improved outcome. In fact, large myocardial infarctions (MIs) have been associated with pronounced adv...
متن کامل“Rusty Hearts”
Rapidly restoring blood flow in the epicardial coronary artery after an acute obstruction is critical for limiting myocardial tissue damage and salvaging the area at risk. Minimizing the acute injury to the myocardium after an ischemic event (ie, infarct size) has been strongly correlated with improved outcome. In fact, large myocardial infarctions (MIs) have been associated with pronounced adv...
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ژورنال
عنوان ژورنال: Nature Reviews Drug Discovery
سال: 2004
ISSN: 1474-1776,1474-1784
DOI: 10.1038/nrd1355